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| Monday, September 29th , 2025 |
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| Mississippi Firebirds: SP Tony Holmes retired from professional baseball. |
| Birmingham Barons: SP Don Young retired from professional baseball. |
| Jackson Generals: LF Joe Clark retired from professional baseball. |
| Pensacola Blue Wahoos: RP Ned Childers retired from professional baseball. |
| Pensacola Blue Wahoos: SP Doug Merkel retired from professional baseball. |
| Tennessee Smokies: CF Duane Baker retired from professional baseball. |
| Montgomery Biscuits: CF Steve Stover retired from professional baseball. |
| Birmingham Barons: SP José Aguilera retired from professional baseball. |
| Biloxi Shuckers: RF Anderson Castro retired from professional baseball. |
| Jackson Generals: RP Danny Moore retired from professional baseball. |
| Pensacola Blue Wahoos: SP Chris Whitaker retired from professional baseball. |
| Montgomery Biscuits: C Eric Mahoney retired from professional baseball. |
| Montgomery Biscuits: CL Horace Cook retired from professional baseball. |
| Mississippi Firebirds: RP Ed Sanders retired from professional baseball. |
| Jackson Generals: RP Pat Sellers retired from professional baseball. |
| Biloxi Shuckers: 2B Jeff Walker retired from professional baseball. |
| Jackson Generals: LF Cristián Martínez retired from professional baseball. |
| Pensacola Blue Wahoos: SP Bruno Quinn retired from professional baseball. |
| Biloxi Shuckers: SP Bob Hunter retired from professional baseball. |
| Mississippi Firebirds: SP Jim Wade retired from professional baseball. |
| Mobile BayBears: SP Juan Carlos Gutiérrez retired from professional baseball. |
| Jacksonville Suns: C Eric Adams retired from professional baseball. |
| Tennessee Smokies: 1B Jeff Allen retired from professional baseball. |
| Montgomery Biscuits: RP Kevin Morrow retired from professional baseball. |
| Birmingham Barons: 2B Jim MacIntyre retired from professional baseball. |
| Mississippi Firebirds: C Greg Simmons retired from professional baseball. |
| Montgomery Biscuits: 3B Ted Brown retired from professional baseball. |
| Mobile BayBears: RF Chris Bennett retired from professional baseball. |
| Birmingham Barons: Hitting Coach Jeff Manto retires. |
| Chattanooga Lookouts: Activated RF António García from the injured list. |
