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| Name | Pos | Team | Age | DOB | POB | Nationality | Bats | Throws | Height | Weight | Salary |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Salazar, António | CL | Eugene Emeralds | 23 | 09/15/2002 | San Juan de la Maguana | DOM | Right | Right | 6' 1" | 190 lbs | - |
| Salcido, Oliver | RP | Hillsboro Hops | 22 | 06/24/2003 | Valencia | VEN | Right | Right | 6' 1" | 180 lbs | - |
| Saldaña, Rodrigo | SP | Everett AquaSox | 21 | 06/10/2004 | Santo Domingo | DOM | Right | Right | 6' 3" | 175 lbs | - |
| Salinas, José | SS | Free Agent | 21 | 02/11/2004 | Maracay | VEN | Switch | Right | 6' 2" | 180 lbs | - |
| Santístevan, Albert | LF | Tri-City Dust Devils | 22 | 09/20/2003 | Carson City | USA | Left | Left | 6' 2" | 200 lbs | - |
| Saro, Rinaldo | SP | Eugene Emeralds | 22 | 09/16/2003 | Los Dos Caminos | VEN | Left | Left | 6' 1" | 175 lbs | - |
| Schmitt, Tom | SP | Hillsboro Hops | 24 | 03/07/2001 | Vancouver | CAN | Right | Right | 6' 4" | 205 lbs | - |
| Scott, Ron | RP | Boise Hawks | 23 | 10/13/2002 | Chula Vista | USA | Switch | Right | 6' 0" | 185 lbs | - |
| Sheets, Kevin | C | Everett AquaSox | 22 | 12/04/2002 | Friendswood | USA | Right | Right | 6' 1" | 195 lbs | - |
| Shirley, Bobby | 2B | Vancouver Canadians | 23 | 11/28/2001 | Hopkinton | USA | Right | Right | 6' 1" | 195 lbs | - |
| Short, Duane | SP | Vancouver Canadians | 22 | 02/06/2003 | Phoenix | USA | Right | Right | 6' 3" | 190 lbs | - |
| Smith, Brendan | C | Hillsboro Hops | 19 | 11/22/2005 | Los Angeles | USA | Left | Right | 6' 0" | 195 lbs | - |
| Soleana, Cerilio | RP | Free Agent | 28 | 04/22/1997 | Unknown | ANT | Left | Left | 5' 11" | 185 lbs | - |
| St. John, Steve | SP | Salem-Keizer Volcanoes | 20 | 01/07/2005 | Ceres | USA | Right | Right | 6' 2" | 190 lbs | - |
| Steele, Jeremiah | SP | Everett AquaSox | 23 | 08/12/2002 | Phoenix | USA | Left | Left | 5' 10" | 165 lbs | - |
| Stover, Tim | RP | Tri-City Dust Devils | 21 | 03/29/2004 | Santa Ana | USA | Right | Right | 6' 2" | 185 lbs | - |
| Stroud, Joe | RP | Vancouver Canadians | 23 | 03/24/2002 | Nashville | USA | Right | Right | 5' 10" | 175 lbs | - |
| Sullivan, Toby | RP | Tri-City Dust Devils | 23 | 09/30/2002 | Bellevue | USA | Left | Left | 6' 4" | 205 lbs | - |
| Sutton, Ron | SP | Salem-Keizer Volcanoes | 23 | 04/25/2002 | Aubrey | USA | Right | Right | 6' 0" | 195 lbs | - |
| Sánchez, César | SP | Hillsboro Hops | 20 | 11/09/2004 | Barinas | VEN | Left | Right | 6' 7" | 200 lbs | - |
| Sánchez, Manny | CF | Tri-City Dust Devils | 20 | 03/03/2005 | Santo Domingo | DOM | Left | Left | 6' 2" | 185 lbs | - |
