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| Monday, August 11th , 2025 |
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| Activated LF Orlando Silva from the injured list. |
| Monday, August 4th , 2025 |
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| Placed LF Orlando Silva on the 7-day injured list, retroactive to 08/03/2025. |
| Friday, July 18th , 2025 |
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| SP Jeferson Mejia was designated for assignment. |
| Tuesday, June 24th , 2025 |
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| Activated RP Pat Poe from the injured list. |
| Thursday, May 22nd , 2025 |
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| Activated SP Tim Brown from the injured list. |
| Placed SP António Fernández on the 7-day injured list, retroactive to 05/20/2025. |
| Tuesday, April 15th , 2025 |
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| Placed SP Tim Brown on the 7-day injured list, retroactive to 04/13/2025. |
| Thursday, April 10th , 2025 |
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| Received SP Emilio Ferrebus from Double A Birmingham. |
| Received SP Don Young from Double A Birmingham. |
| Received SP Héctor Ochoa from Double A Birmingham. |
| Received SP Ron Lyons from High A Winston-Salem. |
| Received SP Chris Phillips from Double A Birmingham. |
| Demoted RP Jose A. Suarez to Double A Birmingham. |
| Demoted RP Rubén Romero to Double A Birmingham. |
| Demoted 1B José Quintana to Double A Birmingham. |
| Demoted 1B Joe Morgan to Double A Birmingham. |
| Demoted RP Carlos Bennett to High A Winston-Salem. |
| Received SP Jimmy Stanley from High A Winston-Salem. |
| Received SP José Aguilera from Double A Birmingham. |
| Demoted RP Ken Williams to Double A Birmingham. |
| Demoted RP Pat Poe to High A Winston-Salem. |
| Friday, March 21st , 2025 |
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| Received RP Luis Chavarría from Major League Chicago. |
| Tuesday, March 4th , 2025 |
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| Promoted SP Jesús Martínez to Major League Chicago. |
| Promoted CF Juan Ramos to Major League Chicago. |
| Promoted 2B Wendell Rijo to Major League Chicago. |
| Promoted SS Luis Mejia to Major League Chicago. |
| Promoted 3B Wes Stevens to Major League Chicago. |
| Promoted 3B Felix Mercedes to Major League Chicago. |
| Promoted C Raúl Ruíz to Major League Chicago. |
| Promoted RP Yeferson Ardiles to Major League Chicago. |
| Promoted RP Don Young to Major League Chicago. |
| Promoted SP Emilio Ferrebus to Major League Chicago. |
| Promoted CF Alfredo Martínez to Major League Chicago. |
| Monday, December 2nd , 2024 |
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| CF Bob Lyons becomes a free-agent. |
| Saturday, November 30th , 2024 |
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| RP Connor Walsh becomes a free-agent. |
| Wednesday, September 25th , 2024 |
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| C Ken Miller retired from professional baseball. |
| RP Wilbert Nash retired from professional baseball. |
| SP Dana Campbell retired from professional baseball. |
| SP Yency Almonte retired from professional baseball. |
| 3B Anderson Franco retired from professional baseball. |
| RP Chris Freudenberg retired from professional baseball. |
| RP Takumi Numata retired from professional baseball. |
| RP Rodrigo Takahashi retired from professional baseball. |
| RP Argemiro Estremor retired from professional baseball. |
| C Carlos J. Perez retired from professional baseball. |
| RP Curt Greene retired from professional baseball. |
| RP Dave Brown retired from professional baseball. |
