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| Friday, November 21st , 2025 |
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| Daytona Tortugas: Signed Manager Tracy McGrady. |
| Tuesday, November 18th , 2025 |
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| Jupiter Hammerheads: Signed - Mike Johnston to a 3-year contract extension. |
| Thursday, November 13th , 2025 |
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| Brevard County Manatees: Signed Manager Jeremy Hernandez. |
| Wednesday, November 12th , 2025 |
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| Tampa Yankees: Signed Manager Justin Smoak. |
| Saturday, November 1st , 2025 |
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| RP Héctor Sandoval retired from professional baseball. |
| RP Luis Ledesma retired from professional baseball. |
| RP Gilberto Chu retired from professional baseball. |
| RP Mario García retired from professional baseball. |
| LF Zorg Rosler retired from professional baseball. |
| RF Greg Brown retired from professional baseball. |
| RP Ron Brown retired from professional baseball. |
| SS Bob Maddox retired from professional baseball. |
| RP Dimacali Benaoro retired from professional baseball. |
| RP Bob Price retired from professional baseball. |
| RP Leon Olsen retired from professional baseball. |
| SS Kevin Bell retired from professional baseball. |
| 2B Ken Small retired from professional baseball. |
| LF Ed Keith retired from professional baseball. |
| RP Bob Day retired from professional baseball. |
| LF Jeremiah Stephens retired from professional baseball. |
| 2B Randy O'Keenan retired from professional baseball. |
| 2B Hsi-men Cheng retired from professional baseball. |
| RP César Martínez retired from professional baseball. |
| LF Greg Haines retired from professional baseball. |
| RP Miika Puumalainen retired from professional baseball. |
| Dunedin Blue Jays: Pitching Coach Bob Milacki retires. |
| Manager Tim Esmay retires. |
| Hitting Coach John Mayberry Jr. retires. |
| Hitting Coach Shawn Abner retires. |
| Hitting Coach Leo Gomez retires. |
| Manager Eli Marrero retires. |
| Hitting Coach Peter Maestrales retires. |
| Hitting Coach Ramon Nivar retires. |
| Hitting Coach Billy Horton retires. |
| Manager Kazuo Hayakawa retires. |
| Manager Dan Lowe retires. |
| Charlotte Stone Crabs: Pitching Coach Jairo Cuevas leaves the team, his contract was not renewed |
| Charlotte Stone Crabs: Hitting Coach Sixto Ortega leaves the team, his contract was not renewed |
| Dunedin Blue Jays: Manager Caden Smith leaves the team, his contract was not renewed |
| St. Lucie Mets: Pitching Coach Johnny Holtom leaves the team, his contract was not renewed |
| Clearwater Threshers: Pitching Coach Scott Klingenbeck leaves the team, his contract was not renewed |
| Daytona Tortugas: Hitting Coach Fernando Prado leaves the team, his contract was not renewed |
| Daytona Tortugas: Manager Mac Stewart leaves the team, his contract was not renewed |
| Daytona Tortugas: Pitching Coach Brandon Beachy leaves the team, his contract was not renewed |
| Brevard County Manatees: Manager Allen Craig leaves the team, his contract was not renewed |
| Palm Beach Cardinals: Hitting Coach Bryan Petersen leaves the team, his contract was not renewed |
| Palm Beach Cardinals: Pitching Coach Scott Elbert leaves the team, his contract was not renewed |
| Saturday, September 27th , 2025 |
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| Fort Myers Miracle: Activated LF Raúl Molina from the injured list. |
| Fort Myers Miracle: Activated RF Joe Collins from the injured list. |
| Thursday, September 25th , 2025 |
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| Charlotte Stone Crabs: RF Jeff Viitaluoma retired from professional baseball. |
| Daytona Tortugas: LF Yeong-seon Lee retired from professional baseball. |
| Charlotte Stone Crabs: RP Guadalupe Chavez retired from professional baseball. |
| Dunedin Blue Jays: RP Kevin McGhee retired from professional baseball. |
| Daytona Tortugas: RP Bob Dillon retired from professional baseball. |
| St. Lucie Mets: C Bob Williams retired from professional baseball. |
| Bradenton Marauders: CF Dave Sherman retired from professional baseball. |
| Lakeland Flying Tigers: CF Dave Murphy retired from professional baseball. |
| Bradenton Marauders: RP Joe Wolfe retired from professional baseball. |
| St. Lucie Mets: CF Luis Carmona retired from professional baseball. |
| Clearwater Threshers: 2B Chad Starr retired from professional baseball. |
| Charlotte Stone Crabs: RP Lou Woods retired from professional baseball. |
| St. Lucie Mets: SS Alan Lucas retired from professional baseball. |
| Daytona Tortugas: 3B Jeff Stewart retired from professional baseball. |
| Daytona Tortugas: LF Vince Rabe retired from professional baseball. |
| Charlotte Stone Crabs: RP Don Hart retired from professional baseball. |
| St. Lucie Mets: 1B Brad Oglethorpe retired from professional baseball. |
| Lakeland Flying Tigers: C Pat Christenson retired from professional baseball. |
| Lakeland Flying Tigers: RP Jeremy Harvey retired from professional baseball. |
| St. Lucie Mets: RP Eric Webster retired from professional baseball. |
| Dunedin Blue Jays: 2B Cal Bocanegra retired from professional baseball. |
| Fort Myers Miracle: RP Ken Butler retired from professional baseball. |
| Bradenton Marauders: C Bob Thompson retired from professional baseball. |
| Fort Myers Miracle: RP Steve Gray retired from professional baseball. |
| St. Lucie Mets: RP Darryl Stone retired from professional baseball. |
| Bradenton Marauders: C Dave Weeks retired from professional baseball. |
| Palm Beach Cardinals: RP Wing-chiu Huang retired from professional baseball. |
| Lakeland Flying Tigers: RP Enzo Garin retired from professional baseball. |
| Dunedin Blue Jays: LF Willie Hawkins retired from professional baseball. |
| Clearwater Threshers: RP Steve Black retired from professional baseball. |
| Clearwater Threshers: C Oscar Stanton retired from professional baseball. |
| Jupiter Hammerheads: SP Bobby Harris retired from professional baseball. |
