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| Name | Pos | Team | Age | DOB | POB | Nationality | Bats | Throws | Height | Weight | Salary |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Sackett, Dylan | SS | Kansas City (AZL) Royals | 19 | 07/30/2006 | Brooklyn | USA | Right | Right | 6' 3" | 180 lbs | - |
| Sanders, Art | 2B | Arizona (AZL) Diamondbacks | 20 | 02/04/2005 | Columbia | USA | Switch | Right | 5' 10" | 160 lbs | - |
| Sandoval, Pat | CF | Los Angeles N (AZL) Dodgers | 21 | 08/26/2004 | Bristol | USA | Left | Left | 6' 2" | 175 lbs | - |
| Santana, Cristo | SP | San Diego (AZL) Padres | 17 | 05/04/2008 | Carúpano | VEN | Right | Right | 6' 1" | 170 lbs | - |
| Santos, Freddy | RP | Chicago A (AZL) White Sox | 19 | 10/01/2006 | Santo Domingo | DOM | Left | Left | 6' 0" | 165 lbs | - |
| Santos, Jorge | SP | Free Agent | 20 | 03/29/2005 | San Juan | PUR | Left | Right | 6' 2" | 175 lbs | - |
| Saunders, Charlie | CF | Texas (AZL) Rangers | 23 | 09/28/2002 | St. Louis | USA | Right | Right | 6' 4" | 200 lbs | - |
| Sawyer, Mike | C | Oakland (AZL) Athletics | 18 | 06/22/2007 | Alturas | USA | Switch | Right | 6' 1" | 200 lbs | - |
| Sewitt, Ben | C | Seattle (AZL) Mariners | 20 | 05/28/2005 | Santa Clarita | USA | Right | Right | 6' 0" | 185 lbs | - |
| Seymour, Ed | 2B | Oakland (AZL) Athletics | 20 | 11/15/2004 | Plano | USA | Right | Right | 6' 0" | 180 lbs | - |
| Seánez, Bernardo | SP | Los Angeles A (AZL) Angels | 20 | 08/30/2005 | Azua | DOM | Left | Left | 6' 1" | 170 lbs | - |
| Simon, Bob | CF | Chicago A (AZL) White Sox | 19 | 08/08/2006 | Englewood | USA | Right | Right | 6' 1" | 180 lbs | - |
| Sinclair, Bob | 3B | Oakland (AZL) Athletics | 19 | 10/06/2006 | Phoenix | USA | Right | Right | 6' 0" | 175 lbs | - |
| Smith, Eric | 3B | Cincinnati (AZL) Reds | 20 | 12/27/2004 | Bear | USA | Switch | Right | 6' 2" | 190 lbs | - |
| Smith, Jarred | SP | Los Angeles A (AZL) Angels | 20 | 10/16/2004 | Wilmington | USA | Left | Right | 6' 2" | 180 lbs | - |
| Sousa, Luis | SP | Milwaukee (AZL) Brewers | 18 | 05/24/2007 | Santa Paula | USA | Left | Left | 6' 2" | 175 lbs | - |
| Spivey, Dorian | 2B | Chicago A (AZL) White Sox | 24 | 07/28/2001 | Helena | USA | Right | Right | 6' 2" | 205 lbs | - |
| Stevens, Scotty | SP | Cleveland (AZL) Guardians | 21 | 01/21/2004 | Concord | USA | Switch | Right | 6' 6" | 205 lbs | - |
| Sullivan, Lou | CF | Cincinnati (AZL) Reds | 22 | 07/17/2003 | Englewood | USA | Right | Right | 6' 4" | 200 lbs | - |
| Sánchez, Juan | C | Kansas City (AZL) Royals | 20 | 11/07/2004 | Estebanía | DOM | Left | Right | 6' 5" | 210 lbs | - |
| Sánchez, Pepe | 2B | Milwaukee (AZL) Brewers | 20 | 10/11/2004 | Barinas | VEN | Switch | Right | 6' 0" | 190 lbs | - |
| Sánchez, Raúl | RP | San Diego (AZL) Padres | 20 | 04/05/2005 | Guane | CUB | Left | Left | 6' 2" | 185 lbs | - |
| Sánchez, Álex | C | Los Angeles N (AZL) Dodgers | 17 | 03/04/2008 | Valencia | VEN | Right | Right | 5' 10" | 175 lbs | - |
