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| Name | Pos | Team | Age | DOB | POB | Nationality | Bats | Throws | Height | Weight | Salary |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Sanford, Mike | RP | Modesto Nuts | 26 | 04/14/2000 | Carrollton | USA | Right | Right | 6' 0" | 200 lbs | - |
| Saul, Mike | CF | Visalia Rawhide | 25 | 12/23/2000 | Winter Garden | USA | Right | Right | 6' 2" | 200 lbs | - |
| Schneider, Jake | RF | Bakersfield Blaze | 24 | 05/20/2001 | Throop | USA | Left | Left | 6' 0" | 190 lbs | - |
| Schroeder, Rob | SP | San Jose Giants | 24 | 06/27/2001 | Van Buren | USA | Left | Left | 5' 11" | 180 lbs | - |
| Schultz, Bobby | 2B | High Desert Mavericks | 27 | 02/21/1999 | Jackson | USA | Left | Right | 6' 0" | 185 lbs | - |
| Seals, Sean | RF | San Jose Giants | 23 | 05/17/2002 | Austin | USA | Left | Left | 6' 4" | 205 lbs | - |
| Segura, Julián | SP | Rancho Cucamonga Quakes | 22 | 10/21/2003 | Santo Domingo | DOM | Right | Right | 6' 1" | 185 lbs | - |
| Sheeran, Sam | SP | Free Agent | 26 | 03/23/2000 | Columbus | USA | Right | Right | 6' 3" | 200 lbs | - |
| Shelton, Jeff | SP | Lancaster JetHawks | 22 | 09/05/2003 | Leavenworth | USA | Left | Left | 6' 0" | 185 lbs | - |
| Sheng, Luo-shan | C | Stockton Ports | 26 | 03/11/2000 | Meinung | TPE | Left | Right | 6' 0" | 205 lbs | - |
| Silva, Mike | SS | Inland Empire 66ers | 20 | 12/20/2005 | Madison | USA | Right | Right | 6' 3" | 185 lbs | - |
| Simmons, Gene | C | High Desert Mavericks | 21 | 09/17/2004 | Clear Lake | USA | Right | Right | 5' 11" | 200 lbs | - |
| Skouloudis, Timon | SP | Lancaster JetHawks | 24 | 06/10/2001 | Concord | USA | Right | Right | 6' 0" | 180 lbs | - |
| Smith, Caleb | SP | Inland Empire 66ers | 21 | 02/19/2005 | Rochester | USA | Left | Left | 6' 0" | 180 lbs | - |
| Smith, Colt | SP | Free Agent | 27 | 07/24/1998 | Lochearn | USA | Right | Right | 6' 4" | 200 lbs | - |
| Smith, Ken | CL | Rancho Cucamonga Quakes | 23 | 08/30/2002 | New York | USA | Switch | Right | 6' 4" | 210 lbs | - |
| Smith, Robby | RP | High Desert Mavericks | 23 | 02/17/2003 | Bergenfield | USA | Right | Right | 5' 10" | 170 lbs | - |
| Smith, Tim | C | Rancho Cucamonga Quakes | 26 | 02/27/2000 | Bloomfield Township | USA | Right | Right | 6' 4" | 240 lbs | - |
| Soto, Pancho | SS | San Jose Giants | 25 | 09/19/2000 | Hemphill | USA | Right | Right | 6' 2" | 200 lbs | - |
| Spencer, Dana | CF | Bakersfield Blaze | 23 | 05/31/2002 | Temple | USA | Left | Left | 6' 0" | 195 lbs | - |
| Sweet, Chris | C | Inland Empire 66ers | 23 | 11/17/2002 | Urbandale | USA | Right | Right | 6' 1" | 200 lbs | - |
| Sáenz, Raúl | C | Free Agent | 25 | 05/06/2001 | Caguas | PUR | Left | Right | 5' 10" | 190 lbs | - |
| Sánchez, Sergio | RF | Rancho Cucamonga Quakes | 22 | 11/06/2003 | Russellville | USA | Left | Left | 6' 1" | 195 lbs | - |
| Sánchez, Víctor | RP | High Desert Mavericks | 24 | 07/05/2001 | Ft. Payne | USA | Right | Right | 6' 0" | 190 lbs | - |
